Sparsomycin Exhibits Potent Antiplasmodial Activity In Vitro and In Vivo

The emerging spread of drug-resistant malaria parasites highlights the need for new antimalarial agents. This study evaluated the growth-inhibitory effects of sparsomycin (Sm), a peptidyl transferase inhibitor, against <i>Plasmodium falciparum</i> 3D7 (chloroquine-sensitive strain), <...

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Bibliographic Details
Main Authors: Nanang Rudianto Ariefta, Baldorj Pagmadulam, Coh-ichi Nihei, Yoshifumi Nishikawa
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/14/3/544