Advanced Paternal Age and Sperm DNA Fragmentation: A Systematic Review

Purpose: Male ageing is often associated with defective sperm DNA remodeling mechanisms that result in poorly packaged chromatin and a decreased ability to repair DNA strand breaks. However, the impact of advanced paternal age on DNA fragmentation remains inconclusive. The aim of the present syste...

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Bibliographic Details
Main Authors: Daniel C. Gonzalez, Jesse Ory, Ruben Blachman-Braun, Sirpi Nackeeran, Jordan C. Best, Ranjith Ramasamy
Format: Article
Language:English
Published: Korean Society for Sexual Medicine and Andrology 2022-01-01
Series:The World Journal of Men's Health
Subjects: