Investigations into the Toxicology of Spirolides, a Group of Marine Phycotoxins

Investigations into the Toxicology of Spirolides, a Group of Marine Phycotoxins

Spirolides are marine phycotoxins produced by the dinoflagellates Alexandrium ostenfeldii and A. peruvianum. Here we report that 13-desmethyl spirolide C shows little cytotoxicity when incubated with various cultured mammalian cell lines. When administered to mice by intraperitoneal (ip) injection,...

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Bibliographic Details
Main Authors: Rex Munday, Shawna L. MacKinnon, H. Stephen Ewart, Sandra A. Sperker, Pamela Gallant, Nancy Lewis, Patricia LeBlanc, Michael A. Quilliam
Format: Article
Language:English
Published: MDPI AG 2011-12-01
Series:Toxins
Subjects:
spirolides
marine phycotoxin
acute toxicity
Alexandrium ostenfeldii
seafood poisoning
Online Access:http://www.mdpi.com/2072-6651/4/1/1/

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http://www.mdpi.com/2072-6651/4/1/1/

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