VEGFR3 is required for button junction formation in lymphatic vessels

Summary: Lymphatic capillaries develop discontinuous cell-cell junctions that permit the absorption of large macromolecules, chylomicrons, and fluid from the interstitium. While excessive vascular endothelial growth factor 2 (VEGFR2) signaling can remodel and seal these junctions, whether and how VE...

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Bibliographic Details
Main Authors: Melanie Jannaway, Drishya Iyer, Diandra M. Mastrogiacomo, Kunyu Li, Derek C. Sung, Ying Yang, Mark L. Kahn, Joshua P. Scallan
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472300788X