Targeting tumor-associated macrophages in hepatocellular carcinoma: biology, strategy, and immunotherapy

Abstract Hepatocellular carcinoma (HCC), one of the most malignant tumors, is characterized by its stubborn immunosuppressive microenvironment. As one of the main members of the tumor microenvironment (TME) of HCC, tumor-associated macrophages (TAMs) play a critical role in its occurrence and develo...

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Bibliographic Details
Main Authors: Hongyu Zheng, Xueqiang Peng, Shuo Yang, Xinyu Li, Mingyao Huang, Shibo Wei, Sheng Zhang, Guangpeng He, Jiaxing Liu, Qing Fan, Liang Yang, Hangyu Li
Format: Article
Language:English
Published: Nature Publishing Group 2023-02-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01356-7