PLAAT1 inhibits type I interferon response via degradation of IRF3 and IRF7 in Zebrafish

PLAAT1 inhibits type I interferon response via degradation of IRF3 and IRF7 in Zebrafish

PLAAT1 is a member of the PLAAT protein family and plays important roles in tumor suppression, transglutaminase activation and peroxisomal biogenesis. Recently, PLAAT1 has been shown to promote degradation of p53 protein and cellular organelles such as mitochondria, endoplasmic reticulum and lysosom...

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Bibliographic Details
Main Authors: Xin Zhao, Wenji Huang, Yanjie Shi, Jiahong Guo, Hehe Xiao, Ning Ji, Jianhua Feng, Huifeng Dang, Jun Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
PLAAT1
IRF3
IRF7
interferon
autophagy
virus
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.979919/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.979919/full

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