A genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in Kenya.

A genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in Kenya.

Drug resistance remains a chief concern for malaria control. In order to determine the genetic markers of drug resistant parasites, we tested the genome-wide associations (GWA) of sequence-based genotypes from 35 Kenyan P. falciparum parasites with the activities of 22 antimalarial drugs.Parasites i...

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Bibliographic Details
Main Authors: Jason P Wendler, John Okombo, Roberto Amato, Olivo Miotto, Steven M Kiara, Leah Mwai, Lewa Pole, John O'Brien, Magnus Manske, Dan Alcock, Eleanor Drury, Mandy Sanders, Samuel O Oyola, Cinzia Malangone, Dushyanth Jyothi, Alistair Miles, Kirk A Rockett, Bronwyn L MacInnis, Kevin Marsh, Philip Bejon, Alexis Nzila, Dominic P Kwiatkowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4014544?pdf=render

Internet

http://europepmc.org/articles/PMC4014544?pdf=render

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