Anopheles stephensi p38 MAPK signaling regulates innate immunity and bioenergetics during Plasmodium falciparum infection

Anopheles stephensi p38 MAPK signaling regulates innate immunity and bioenergetics during Plasmodium falciparum infection

Abstract Background Fruit flies and mammals protect themselves against infection by mounting immune and metabolic responses that must be balanced against the metabolic needs of the pathogens. In this context, p38 mitogen-activated protein kinase (MAPK)-dependent signaling is critical to regulating b...

Full description

Bibliographic Details
Main Authors: Bo Wang, Nazzy Pakpour, Eleonora Napoli, Anna Drexler, Elizabeth K. K. Glennon, Win Surachetpong, Kong Cheung, Alejandro Aguirre, John M. Klyver, Edwin E. Lewis, Richard Eigenheer, Brett S. Phinney, Cecilia Giulivi, Shirley Luckhart
Format: Article
Language:English
Published: BMC 2015-08-01
Series:Parasites & Vectors
Subjects:
Malaria
Mitochondria
Innate immunity
Mitogen-activated protein kinase
MAPK
p38
Online Access:https://doi.org/10.1186/s13071-015-1016-x

Internet

https://doi.org/10.1186/s13071-015-1016-x

Similar Items