Obese mammary tumour-bearing mice are highly sensitive to doxorubicin-induced hepatotoxicity
Abstract Background Breast cancer is a major health burden for women, worldwide. Lifestyle-related risk factors, such as obesity and being overweight, have reached epidemic proportions and contributes to the development of breast cancer. Doxorubicin (DXR) is a chemotherapeutic drug commonly used to...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-11-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12885-022-10189-z |