Tacrolimus’s Time Below Therapeutic Range Is Associated With Acute Pancreatic Graft Rejection and the Development of De Novo Donor-specific Antibodies

Tacrolimus’s Time Below Therapeutic Range Is Associated With Acute Pancreatic Graft Rejection and the Development of De Novo Donor-specific Antibodies

Tacrolimus is pivotal in pancreas transplants but poses challenges in maintaining optimal levels due to recipient differences. This study aimed to explore the utility of time spent below the therapeutic range and intrapatient variability in predicting rejection and de novo donor-specific antibody (d...

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Bibliographic Details
Main Authors: Diana Rodríguez-Espinosa, José Jesús Broseta, Enrique Montagud-Marrahí, Carolt Arana, Joana Ferrer, Miriam Cuatrecasas, Ángeles Garcia-Criado, Antonio J. Amor, Fritz Diekmann, Pedro Ventura-Aguiar
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Transplant International
Subjects:
pancreas transplantation
tacrolimus
FK
time in therapeutic range
TTR
Online Access:https://www.frontierspartnerships.org/articles/10.3389/ti.2024.12591/full

Internet

https://www.frontierspartnerships.org/articles/10.3389/ti.2024.12591/full

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