Targeting the Ubiquitylation and ISGylation Machinery for the Treatment of COVID-19

Targeting the Ubiquitylation and ISGylation Machinery for the Treatment of COVID-19

Ubiquitylation and ISGylation are protein post-translational modifications (PTMs) and two of the main events involved in the activation of pattern recognition receptor (PRRs) signals allowing the host defense response to viruses. As with similar viruses, SARS-CoV-2, the virus causing COVID-19, hijac...

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Bibliographic Details
Main Authors: George Vere, Md Rashadul Alam, Sam Farrar, Rachel Kealy, Benedikt M. Kessler, Darragh P. O’Brien, Adán Pinto-Fernández
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomolecules
Subjects:
SARS-CoV-2
COVID-19
ubiquitin proteasome system
ISGylation
ubiquitomics
Online Access:https://www.mdpi.com/2218-273X/12/2/300

Internet

https://www.mdpi.com/2218-273X/12/2/300

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