Smurf2-induced degradation of SMAD2 causes inhibition of hair follicle stem cell differentiation

Abstract Hair follicle stem cells (HFSCs) are implicated in the formation of hair follicles and epidermis. This study aims to clarify the role of SMAD2 in regulating the differentiation of HFSCs, which is involved with Smurf2. Functional assays were carried out in human HFSCs to assess the effect of...

Full description

Bibliographic Details
Main Authors: Bojie Lin, Dan Huang, Guanyu Lin, Yong Miao, Jin Wang, Zhexiang Fan, Zhiqi Hu
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-00920-x