Smurf2-induced degradation of SMAD2 causes inhibition of hair follicle stem cell differentiation
Abstract Hair follicle stem cells (HFSCs) are implicated in the formation of hair follicles and epidermis. This study aims to clarify the role of SMAD2 in regulating the differentiation of HFSCs, which is involved with Smurf2. Functional assays were carried out in human HFSCs to assess the effect of...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-04-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-022-00920-x |