Evaluation of vascular aging on measures of cardiac function and mechanical efficiency: insights from in-silico modeling

Evaluation of vascular aging on measures of cardiac function and mechanical efficiency: insights from in-silico modeling

IntroductionThis study evaluated the hypothesis that vascular aging (VA) reduces ventricular contractile function and mechanical efficiency (ME) using the left ventricular pressure-volume (PV) construct.MethodsA previously published in-silico computational model (CM) was modified to evaluate the hyp...

Full description

Bibliographic Details
Main Authors: Lawrence J. Mulligan, Julian Thrash, Ludmil Mitrev, Douglas Folk, Alyssa Exarchakis, Daniel Ewert, Jeffrey C. Hill
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
computational model
vascular aging
mechanical efficiency
pressure-volume area
aortic compliance
ventricular-vascular coupling
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2024.1351484/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2024.1351484/full

Similar Items