Inositol polyphosphate multikinase deficiency leads to aberrant induction of synaptotagmin-2 in the forebrain

Abstract Inositol polyphosphate multikinase (IPMK), the key enzyme responsible for the synthesis of higher inositol polyphosphates and phosphatidylinositol 3, 4, 5-trisphosphate, is known to mediate various biological events, such as cellular growth and metabolism. Conditional deletion of IPMK in ex...

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Bibliographic Details
Main Authors: Jina Park, Seung Ju Park, Seyun Kim
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Molecular Brain
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13041-019-0480-1