Inositol polyphosphate multikinase deficiency leads to aberrant induction of synaptotagmin-2 in the forebrain
Abstract Inositol polyphosphate multikinase (IPMK), the key enzyme responsible for the synthesis of higher inositol polyphosphates and phosphatidylinositol 3, 4, 5-trisphosphate, is known to mediate various biological events, such as cellular growth and metabolism. Conditional deletion of IPMK in ex...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-06-01
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Series: | Molecular Brain |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13041-019-0480-1 |