Treatment response of advanced HNSCC towards immune checkpoint inhibition is associated with an activated effector memory T cell phenotype
Locally advanced or metastatic head and neck squamous cell carcinoma (HNSCC) is associated with a poor prognosis. The introduction of PD-1 inhibitors has led to a significant improvement in survival, but only a subpopulation of patients responds to therapy. Current biomarkers cannot reliably identif...
Main Authors: | Max Schumacher, Sina Beer, Emmanuelle Moraes Ribeiro, Fulya Korkmaz, Hildegard Keppeler, Rahel Fitzel, Estelle Erkner, Pia Radszuweit, Claudia Lengerke, Corina Schneidawind, Sebastian Hoefert, Paul Stefan Mauz, Dominik Schneidawind |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2024-03-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2024.1333640/full |
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