Oncogenic TRIB2 interacts with and regulates PKM2 to promote aerobic glycolysis and lung cancer cell procession

Oncogenic TRIB2 interacts with and regulates PKM2 to promote aerobic glycolysis and lung cancer cell procession

Abstract PKM2 is an important regulator of the aerobic glycolysis that plays a vital role in cancer cell metabolic reprogramming. In general, Trib2 is considered as a “pseudokinase”, contributing to different kinds of cancer. However, the detailed roles of TRIB2 in regulating cancer metabolism by PK...

Full description

Bibliographic Details
Main Authors: Yuan-Rong Liu, Dan-Dan Song, Dong-Min Liang, You-Jie Li, Yun-Fei Yan, Hong-Fang Sun, Mei-Ling Zhang, Jin-Xia Hu, Yu-Long Zhao, Yan Liang, Yan-Mei Li, Zhen Yang, Ran-Ran Wang, Hou-Feng Zheng, Pingyu Wang, Shu-Yang Xie
Format: Article
Language:English
Published: Nature Publishing Group 2022-07-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01095-1

Internet

https://doi.org/10.1038/s41420-022-01095-1

Similar Items