Circular RNA P4HB promotes glycolysis and tumor progression by binding with PKM2 in lung adenocarcinoma

Circular RNA P4HB promotes glycolysis and tumor progression by binding with PKM2 in lung adenocarcinoma

Abstract Background Emerging evidence indicates that circular RNAs (circRNAs) play vital roles in tumor progression, including lung adenocarcinomas (LUAD). However, the mechanisms by which circRNAs promote the progression of LUAD still require further investigation. Methods Quantitative real-time PC...

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Bibliographic Details
Main Authors: Haoran Li, Haifa Guo, Qi Huang, Shaodong Wang, Xiao Li, Mantang Qiu
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Respiratory Research
Subjects:
Lung adenocarcinoma
circP4HB
PKM2
Macrophage polarization
Aerobic glycolysis
Prognosis
Online Access:https://doi.org/10.1186/s12931-023-02563-7

Internet

https://doi.org/10.1186/s12931-023-02563-7

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