Inferring Gene Dependency Networks from Genomic Longitudinal Data: a Functional Data Approach

A key aim of systems biology is to unravel the regulatory interactions among genes and gene products in a cell. Here we investigate a graphical model that treats the observed gene expression over time as realizations of random curves. This approach is centered around an estimator of dynamical pairw...

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Bibliographic Details
Main Authors: Rainer Opgen-Rhein, Korbinian Strimmer
Format: Article
Language:English
Published: Instituto Nacional de Estatística | Statistics Portugal 2006-03-01
Series:Revstat Statistical Journal
Subjects:
Online Access:https://revstat.ine.pt/index.php/REVSTAT/article/view/26