Short telomere length and its correlation with gene mutations in myelodysplastic syndrome

Short telomere length and its correlation with gene mutations in myelodysplastic syndrome

Abstract Background Telomere erosion can lead to genomic instability and cancer progression. It has been suggested that the shortest telomere, not the average telomere length (TL), is critical for cell viability. Some studies have shown shorter TL in myelodysplastic syndrome (MDS) patients but the c...

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Bibliographic Details
Main Authors: Sang Mee Hwang, Seon Young Kim, Jung Ah Kim, Hee-Sue Park, Si Nae Park, Kyongok Im, Kwantae Kim, Sung-Min Kim, Dong Soon Lee
Format: Article
Language:English
Published: BMC 2016-07-01
Series:Journal of Hematology & Oncology
Subjects:
Telomere length
Quantitative fluorescence in situ hybridization
Single cell
Mutation
Online Access:http://link.springer.com/article/10.1186/s13045-016-0287-9

Internet

http://link.springer.com/article/10.1186/s13045-016-0287-9

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