Diacylglycerol Activates the <i>Drosophila</i> Light Sensitive Channel TRPL Expressed in HEK Cells

Diacylglycerol Activates the <i>Drosophila</i> Light Sensitive Channel TRPL Expressed in HEK Cells

Physiological activation by light of the <i>Drosophila</i> TRP and TRP-like (TRPL) channels requires the activation of phospholipase Cβ (PLC). The hydrolysis of phosphatidylinositol 4,5, bisphosphate (PIP<sub>2</sub>) by PLC is a crucial step in the still-unclear light activa...

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Bibliographic Details
Main Authors: Elisheva Rhodes-Mordov, Tal Brandwine-Shemmer, Rachel Zaguri, Rita Gutorov, Maximilian Peters, Baruch Minke
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Drosophila</i> TRP/TRPL channels
Diacylglycerol (DAG)
1-oleoyl-2-acetyl-sn-glycerol (OAG)
3-hydroxypropane-1,2-diylbis(4-(4-((E)-(4-butylphenyl) diazenyl) phenyl
(OptoDArG)
phospholipase C (PLC)
Online Access:https://www.mdpi.com/1422-0067/24/7/6289

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https://www.mdpi.com/1422-0067/24/7/6289

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