Comparing the expression of human DNA topoisomerase I in KM71H and X33 strains of Pichia pastoris

Background: Human is an essential cellular enzyme that is found in all human cells. As this enzyme is upregulated in cancer cells exceedingly, it is used as a target for cancer chemotherapeutic drug development. As such, producing the in-house enzyme for the purpose to speed up the search for more c...

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Bibliographic Details
Main Authors: Ruo Ping Ang, Leong Sin Teoh, Mooi Kwai Chan, Noorizan Miswan, Boon Yin Khoo
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Electronic Journal of Biotechnology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0717345816000233