ADAM9 Mediates Triple-Negative Breast Cancer Progression via AKT/NF-κB Pathway

ADAM9 Mediates Triple-Negative Breast Cancer Progression via AKT/NF-κB Pathway

Upregulation of a disintegrin and metalloprotease 9 (ADAM9) is correlated with progression of cancers, such as prostate, bladder, and pancreatic cancers. However, its role in triple-negative breast cancer (TNBC) is still unclear. Our study aimed to investigate whether ADAM9 is upregulated and promot...

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Bibliographic Details
Main Authors: Rui Zhou, William C. S. Cho, Victor Ma, Wah Cheuk, Yik-Ka So, S. C. Cesar Wong, Mingrong Zhang, Cong Li, Yujie Sun, Hong Zhang, Lawrence W. C. Chan, Mei Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Medicine
Subjects:
A disintegrin and metalloprotease 9 (ADAM9)
AKT
NF-κB
triple-negative breast cancer (TNBC)
tumor progression
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00214/full

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https://www.frontiersin.org/article/10.3389/fmed.2020.00214/full

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