Pre-analytical sample handling standardization for reliable measurement of metabolites and lipids in LC-MS-based clinical research

Pre-analytical sample handling standardization for reliable measurement of metabolites and lipids in LC-MS-based clinical research

The emerging disciplines of lipidomics and metabolomics show great potential for the discovery of diagnostic biomarkers, but appropriate pre-analytical sample-handling procedures are critical because several analytes are prone to ex vivo distortions during sample collection. To test how the intermed...

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Bibliographic Details
Main Authors: A. Sens, S. Rischke, L. Hahnefeld, E. Dorochow, S.M.G. Schäfer, D. Thomas, M. Köhm, G. Geisslinger, F. Behrens, R. Gurke
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Journal of Mass Spectrometry and Advances in the Clinical Lab
Subjects:
Lipidomics
Metabolomics
K3EDTA plasma sampling
Sampling protocol
Pre-analytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2667145X23000093

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http://www.sciencedirect.com/science/article/pii/S2667145X23000093

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