HIV-Infected Subjects With Poor CD4 T-Cell Recovery Despite Effective Therapy Express High Levels of OX40 and α4β7 on CD4 T-Cells Prior Therapy Initiation

HIV-Infected Subjects With Poor CD4 T-Cell Recovery Despite Effective Therapy Express High Levels of OX40 and α4β7 on CD4 T-Cells Prior Therapy Initiation

BackgroundHIV-infected subjects with suboptimal CD4 restoration despite suppressive combined antiretroviral treatment (cART) (immunodiscordant subjects) have been classically characterized after a variable period of time under cART. Recently, we have reported that an increased frequency of prolifera...

Full description

Bibliographic Details
Main Authors: Isaac Rosado-Sánchez, Inés Herrero-Fernández, Miguel Genebat, Jorge Del Romero, Melchor Riera, Daniel Podzamczer, Julián Olalla, Francesc Vidal, Mª Angeles Muñoz-Fernández, Manuel Leal, Yolanda M. Pacheco
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
immunodiscordant response to combined antiretroviral treatment
low CD4 recovery
homeostatic parameters
homeostatic proliferation
OX40
α4β7
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01673/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01673/full

Similar Items