Transcription of ncRNAs promotes repair of UV induced DNA lesions in Saccharomyces cerevisiae subtelomeres.

Ultraviolet light causes DNA lesions that are removed by nucleotide excision repair (NER). The efficiency of NER is conditional to transcription and chromatin structure. UV induced photoproducts are repaired faster in the gene transcribed strands than in the non-transcribed strands or in transcripti...

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Bibliographic Details
Main Authors: Laetitia Guintini, Audrey Paillé, Marco Graf, Brian Luke, Raymund J Wellinger, Antonio Conconi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-04-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010167