Key Role of Microglial Matrix Metalloproteinases in Choroidal Neovascularization

Key Role of Microglial Matrix Metalloproteinases in Choroidal Neovascularization

Age-related macular degeneration (AMD), especially neovascular AMD with choroidal neovascularization (CNV), is the leading cause of blindness in the elderly. Although matrix metalloproteinases (MMPs) are involved in pathological ocular angiogenesis, including CNV, the cellular origin of MMPs in AMD...

Full description

Bibliographic Details
Main Authors: Juhee Kim, Jong-Heon Kim, Ji Yeon Do, Jung Yi Lee, Ryoji Yanai, In-kyu Lee, Kyoungho Suk, Dong Ho Park
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
age-related macular degeneration (AMD)
choroidal neovascluarization
matrix metalloproteinase
microglia
aqueous humor
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.638098/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2021.638098/full

Similar Items