Immortalization of human neural stem cells with the c-myc mutant T58A.

Human neural stem cells (hNSC) represent an essential source of renewable brain cells for both experimental studies and cell replacement therapies. Their relatively slow rate of proliferation and physiological senescence in culture make their use cumbersome under some experimental and pre-clinical s...

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Bibliographic Details
Main Authors: Lidia De Filippis, Daniela Ferrari, Laura Rota Nodari, Bruno Amati, Evan Snyder, Angelo Luigi Vescovi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2561001?pdf=render