Semi-supervised integration of single-cell transcriptomics data
Abstract Batch effects in single-cell RNA-seq data pose a significant challenge for comparative analyses across samples, individuals, and conditions. Although batch effect correction methods are routinely applied, data integration often leads to overcorrection and can result in the loss of biologica...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-45240-z |