N-acetylcysteine alleviates fine particulate matter (PM2.5)-induced lung injury by attenuation of ROS-mediated recruitment of neutrophils and Ly6Chigh monocytes and lung inflammation

N-acetylcysteine alleviates fine particulate matter (PM2.5)-induced lung injury by attenuation of ROS-mediated recruitment of neutrophils and Ly6Chigh monocytes and lung inflammation

Background: Exposure to particulate matter (PM) may contribute to lung inflammation and injury. The therapeutic effect of N-acetylcysteine (NAC), a well-known antioxidant, with regards to the prevention and treatment of fine PM (PM2.5)-induced lung injury is poorly understood. This study aimed to de...

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Bibliographic Details
Main Authors: Chieh-Mo Lin, Tzu-Hsiung Huang, Miao-Ching Chi, Su-Er Guo, Chiang-Wen Lee, Su-Lun Hwang, Chung-Sheng Shi
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Fine particulate matter
PM-induced lung injury
Ly6Chigh monocyte
N-acetylcysteine
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322004729

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http://www.sciencedirect.com/science/article/pii/S0147651322004729

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