In vitro and in silico evaluation of the schistosomicidal activity of eugenol derivatives using biochemical, molecular, and morphological tools

In vitro and in silico evaluation of the schistosomicidal activity of eugenol derivatives using biochemical, molecular, and morphological tools

Abstract Background Eugenol shows both antibacterial and antiparasitic activities, suggesting that it might be evaluated as an option for the treatment of praziquantel-resistant schistosome. Methods The in vitro activities of three eugenol derivatives (FB1, FB4 and FB9) on adult worms from Schisto...

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Bibliographic Details
Main Authors: Isabella Maria Monteiro de Souza, Romulo Dias Novaes, Reggiani Vilela Gonçalves, Felipe Leonardo Bley Fialho, Diogo Teixeira Carvalho, Thiago Belarmino de Souza, Danielle Ferreira Dias, Stefânia Neiva Lavorato, Raquel Lopes Martins Souza, Marcos José Marques, Aline Pereira Castro
Format: Article
Language:English
Published: SciELO 2022-07-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
Schistosoma mansoni
Eugenol
Schistosomiasis
Mechanism of action
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992022000100314&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992022000100314&tlng=en

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