Changes in the molecular phenotype of nucleus pulposus cells with intervertebral disc aging.

Intervertebral disc (IVD) disorder and age-related degeneration are believed to contribute to low back pain. Cell-based therapies represent a promising strategy to treat disc degeneration; however, the cellular and molecular characteristics of disc cells during IVD maturation and aging still remain...

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Bibliographic Details
Main Authors: Xinyan Tang, Liufang Jing, Jun Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3526492?pdf=render