Analgesic Effect of 5-(3,4-Dihydroxyphenyl)-3-hydroxy-1-(2-hydroxyphenyl)penta-2,4-dien-1-one in Experimental Animal Models of Nociception

Analgesic Effect of 5-(3,4-Dihydroxyphenyl)-3-hydroxy-1-(2-hydroxyphenyl)penta-2,4-dien-1-one in Experimental Animal Models of Nociception

Curcuminoids derived from turmeric rhizome have been reported to exhibit antinociceptive, antioxidant and anti-inflammatory activities. We evaluated the peripheral and central antinociceptive activities of 5-(3,4-dihydroxyphenyl)-3-hydroxy-1-(2-hydroxyphenyl)penta-2,4-dien-1-one (DHHPD), a novel syn...

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Bibliographic Details
Main Authors: Nadhirah Kamarudin, Nadia Hisamuddin, Hui Ming Ong, Ahmad Farhan Ahmad Azmi, Sze Wei Leong, Faridah Abas, Mohd Roslan Sulaiman, Wan Mastura Shaik Mossadeq
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Molecules
Subjects:
pain
5-(3,4-dihydroxyphenyl)-3-hydroxy-1-(2-hydroxyphenyl)penta-2,4-dien-1-one
turmeric
antinociceptive
vanilloid
glutamatergic
opioid
Online Access:http://www.mdpi.com/1420-3049/23/9/2099

Internet

http://www.mdpi.com/1420-3049/23/9/2099

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