ITGB4 deficiency in bronchial epithelial cells directs airway inflammation and bipolar disorder-related behavior

ITGB4 deficiency in bronchial epithelial cells directs airway inflammation and bipolar disorder-related behavior

Abstract Background Chronic persistent airway inflammation has been associated with the comorbidity of asthma and bipolar disorder (BD). However, the direct relevance between airway inflammation and BD-like psychiatric comorbidity is almost unknown. Integrin β4 (ITGB4) is downregulated on the airway...

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Bibliographic Details
Main Authors: Li Han, Leyuan Wang, Sha Tang, Lin Yuan, Shuangyan Wu, Xizi Du, Yang Xiang, Xiangping Qu, Huijun Liu, Huaiqing Luo, Xiaoqun Qin, Chi Liu
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Journal of Neuroinflammation
Subjects:
ITGB4
Bipolar disorder (BD)
Mania
Depression
Microglia
Inflammation
Online Access:http://link.springer.com/article/10.1186/s12974-018-1283-5

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http://link.springer.com/article/10.1186/s12974-018-1283-5

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