Syngeneic Myoblast Transplantation Improves Muscle Function in a Murine Model of X-Linked Myotubular Myopathy

X-linked myotubular myopathy (XLMTM) is an isogenic muscle disease characterized by progressive wasting of skeletal muscle, weakness, and premature death of affected male offspring. Recently, the XLMTM gene knock-in mouse, Mtm1 p.R69C, was found to have a similar phenotype as the MTM1 gene mutation...

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Bibliographic Details
Main Authors: Hyun Ju Lim, Sunyoung Joo, Seh-Hoon Oh, John D. Jackson, Delrae M. Eckman, Tiffaney M. Bledsoe, Christopher R. Pierson, Martin K. Childers, Anthony Atala, James J. Yoo M.D., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2015-09-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368914X683494