NK cell immunopotentiators-loaded nanoliposomes enhance ADCC effect for targeted therapy against HER2-positive breast cancer

NK cell immunopotentiators-loaded nanoliposomes enhance ADCC effect for targeted therapy against HER2-positive breast cancer

Abstract Trastuzumab serves as a cornerstone of first-line therapy for HER2-positive (HER2+) breast cancer; however, a significant challenge arises due to the emergence of resistance within approximately one year of commencement of treatment, particularly in advanced cases with metastatic disease wh...

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Bibliographic Details
Main Authors: Ruoxin Du, Changqing Cao, Dong Fan, Guodong Li, Shuangpeng Pu, Xinyao Xu, Mengmeng Liu, Gege Shi, Yuxin Wu, Qiang Hao, Yuan Gao, Juliang Zhang, Huadong Zhao, Cun Zhang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Cell Communication and Signaling
Subjects:
HER2+ breast cancer
Trastuzumab resistance
Natural killer cell
Antibody-dependent cell-mediated cytotoxicity
Nanoliposomes
Online Access:https://doi.org/10.1186/s12964-024-02023-9

Internet

https://doi.org/10.1186/s12964-024-02023-9

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