Venetoclax inhibits autophagy in chronic lymphocytic leukemia cells

Venetoclax (VCX) is a BCL2 inhibitor approved for treating B cell-derived leukemia, including chronic lymphocytic leukemia (CLL). VCX’s role in apoptosis induction is well-defined, whereas its other mechanistic roles need to be clarified. Autophagy is an intracellular degradation process involving t...

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Bibliographic Details
Main Authors: Yongqiang Chen, Sara E. F. Kost, Xiaoyan Yang, Versha Banerji, James B. Johnston, Sachin Katyal, Spencer B. Gibson
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Autophagy Reports
Subjects:
Online Access:http://dx.doi.org/10.1080/27694127.2023.2169518