Implication of the Association of Fibrinogen Citrullination and Osteoclastogenesis in Bone Destruction in Rheumatoid Arthritis

Immune complexes containing citrullinated fibrinogen are present in the sera and synovium of rheumatoid arthritis patients and potentially contribute to synovitis. However, fibrinogen can inhibit the osteoclastogenesis of precursor cells. We investigated the direct effect of citrullinated fibrinogen...

Full description

Bibliographic Details
Main Authors: Ji Soo Kim, Mikyung Choi, Ji Yong Choi, Joo Yeon Kim, Jeong Yeon Kim, Jin-Su Song, Lionel B. Ivashkiv, Eun Young Lee
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/12/2720