Structural and functional characterization of a complex between the acidic transactivation domain of EBNA2 and the Tfb1/p62 subunit of TFIIH.

Structural and functional characterization of a complex between the acidic transactivation domain of EBNA2 and the Tfb1/p62 subunit of TFIIH.

Infection with the Epstein-Barr virus (EBV) can lead to a number of human diseases including Hodgkin's and Burkitt's lymphomas. The development of these EBV-linked diseases is associated with the presence of nine viral latent proteins, including the nuclear antigen 2 (EBNA2). The EBNA2 pro...

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Bibliographic Details
Main Authors: Philippe R Chabot, Luca Raiola, Mathieu Lussier-Price, Thomas Morse, Genevieve Arseneault, Jacques Archambault, James G Omichinski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3968163?pdf=render

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http://europepmc.org/articles/PMC3968163?pdf=render

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