Dickkopf-1: A Promising Target for Cancer Immunotherapy

Dickkopf-1: A Promising Target for Cancer Immunotherapy

Clinical studies in a range of cancers have detected elevated levels of the Wnt antagonist Dickkopf-1 (DKK1) in the serum or tumors of patients, and this was frequently associated with a poor prognosis. Our analysis of DKK1 gene profile using data from TCGA also proves the high expression of DKK1 in...

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Bibliographic Details
Main Authors: Hang Yin Chu, Zihao Chen, Luyao Wang, Zong-Kang Zhang, Xinhuan Tan, Shuangshuang Liu, Bao-Ting Zhang, Aiping Lu, Yuanyuan Yu, Ge Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
DKK1
cancer
Wnt signaling pathway
immunotherapy
immune surveillance
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.658097/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.658097/full

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