Rational Design for Enhanced Acyltransferase Activity in Water Catalyzed by the <i>Pyrobaculum calidifontis</i> VA1 Esterase

Rational Design for Enhanced Acyltransferase Activity in Water Catalyzed by the <i>Pyrobaculum calidifontis</i> VA1 Esterase

Biocatalytic transesterification is commonly carried out employing lipases in anhydrous organic solvents since hydrolases usually prefer hydrolysis over acyl transfer in bulk water. However, some promiscuous acyltransferases can catalyze acylation in an aqueous solution. In this study, a rational de...

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Bibliographic Details
Main Authors: Amanda Staudt, Henrik Terholsen, Jasmin Kaur, Henrik Müller, Simon P. Godehard, Ivaldo Itabaiana, Ivana C. R. Leal, Uwe T. Bornscheuer
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Microorganisms
Subjects:
PestE
acyltransferase
protein engineering
biocatalysis
acyl transfer
transesterification
Online Access:https://www.mdpi.com/2076-2607/9/8/1790

Internet

https://www.mdpi.com/2076-2607/9/8/1790

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