Resolvin D1/N-formyl peptide receptor 2 ameliorates paclitaxel-induced neuropathic pain through the activation of IL-10/Nrf2/HO-1 pathway in mice

Resolvin D1/N-formyl peptide receptor 2 ameliorates paclitaxel-induced neuropathic pain through the activation of IL-10/Nrf2/HO-1 pathway in mice

IntroductionPaclitaxel is a chemotherapy drug that is commonly used to treat cancer, but it can cause paclitaxel-induced neuropathic pain (PINP) as a side effect. Resolvin D1 (RvD1) has been shown to be effective in promoting the resolution of inflammation and chronic pain. In this study, we evaluat...

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Bibliographic Details
Main Authors: Cun-Jin Su, Jiang-Tao Zhang, Feng-Lun Zhao, De-Lai Xu, Jie Pan, Tong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
RvD1
paclitaxel
FPR2
Il-10
macrophage
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1091753/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1091753/full

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