Validity evaluation of a rat model of monoiodoacetate-induced osteoarthritis with clinically effective drugs

Abstract Background Knee osteoarthritis (KOA) is the most common type of joint disease in elderly people and is characterized by pain and dysfunction. Although the monoiodoacetate (MIA)-induced model is widely used as a rodent KOA model, it is important to acknowledge the inherent limitations of thi...

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Bibliographic Details
Main Authors: Yamato Sasaki, Kei Kijima, Keiji Yoshioka
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Musculoskeletal Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12891-024-08083-9