TNF‐α‐Induced KAT2A Impedes BMMSC Quiescence by Mediating Succinylation of the Mitophagy‐Related Protein VCP

TNF‐α‐Induced KAT2A Impedes BMMSC Quiescence by Mediating Succinylation of the Mitophagy‐Related Protein VCP

Abstract Regular quiescence and activation are important for the function of bone marrow mesenchymal stem cells (BMMSC), multipotent stem cells that are widely used in the clinic due to their capabilities in tissue repair and inflammatory disease treatment. TNF‐α is previously reported to regulate B...

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Bibliographic Details
Main Authors: Zepeng Su, Jinteng Li, Jiajie Lin, Zhikun Li, Yunshu Che, Zhaoqiang Zhang, Guan Zheng, Guiwen Ye, Wenhui Yu, Yipeng Zeng, Peitao Xu, Xiaojun Xu, Zhongyu Xie, Yanfeng Wu, Huiyong Shen
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Advanced Science
Subjects:
BMMSC
mitophagy
quiescence
succinylation
TNF‐α
Online Access:https://doi.org/10.1002/advs.202303388

Internet

https://doi.org/10.1002/advs.202303388

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