Structural requirements and interaction mechanisms of ACE inhibitory peptides: molecular simulation and thermodynamics studies on LAPYK and its modified peptides

The understanding of the structural requirements and the intermolecular-interaction mechanism are important for discovering potent angiotensin-converting enzyme (ACE) inhibitory peptides. In this study, we modified an egg-white derived peptide, LAPYK, using the amino acids with different properties...

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Main Authors: Biying Zhang, Jingbo Liu, Hedi Wen, Feng Jiang, Erlei Wang, Ting Zhang
格式: 文件
语言:English
出版: Tsinghua University Press 2022-11-01
丛编:Food Science and Human Wellness
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在线阅读:http://www.sciencedirect.com/science/article/pii/S2213453022001045