Age Sensitivity of NFκB Abundance and Programmed Cell Death in Erythrocytes Induced by NFκB Inhibitors

Background/Aims: Erythrocytes may enter eryptosis, a suicidal death characterized by cell shrinkage and phosphatidylserine exposure at the erythrocyte outer membrane. Susceptibility to eryptosis is enhanced in aged erythrocytes and stimulated by NFκB-inhibitors Bay 11-7082 and parthenolide....

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Main Authors: Mehrdad Ghashghaeinia, Judith C. Cluitmans, Mahmoud Toulany, Mohammad Saki, Martin Köberle, Elisabeth Lang, Peter Dreischer, Tilo Biedermann, Michael Duszenko, Florian Lang, Giel J. Bosman, Thomas Wieder
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-09-01
Series:Cellular Physiology and Biochemistry
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Online Access:http://www.karger.com/Article/FullText/354481