Immunomodulatory Effect of Proteasome Inhibitors via the Induction of Immunogenic Cell Death in Myeloma Cells

Immunomodulatory Effect of Proteasome Inhibitors via the Induction of Immunogenic Cell Death in Myeloma Cells

Several anti-cancer drugs are known to have immunomodulatory effects, including immunogenic cell death (ICD) of cancer cells. ICD is a form of apoptosis which is caused by the release of damage-associated molecular patterns (DAMPs), the uptake of cancer antigens by dendritic cells, and the activatio...

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Bibliographic Details
Main Authors: Maiko Matsushita, Sho Kashiwazaki, Satoshi Kamiko, Michio Kobori, Makoto Osada, Hisako Kunieda, Maki Hirao, Daiju Ichikawa, Yutaka Hattori
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pharmaceuticals
Subjects:
immunogenic cell death
myeloma
proteasome inhibitors
immunomodulatory
carfilzomib
bortezomib
Online Access:https://www.mdpi.com/1424-8247/16/10/1367

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https://www.mdpi.com/1424-8247/16/10/1367

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