Increased expression of complement regulators CD55 and CD59 on peripheral blood cells in patients with EAHEC O104:H4 infection.

<h4>Background</h4>An outbreak of Shiga Toxin 2 (Stx-2) producing enterohemorrhagic and enteroaggregative E.coli (EAHEC) O104H4 infection in May 2011 caused enterocolitis and an unprecedented high 22% rate of hemolytic uremic syndrome (HUS). The monoclonal anti-C5 antibody Eculizumab (EC...

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Bibliographic Details
Main Authors: Werner Dammermann, Pim Schipper, Sebastian Ullrich, Katharina Fraedrich, Julian Schulze Zur Wiesch, Thorben Fründt, Gisa Tiegs, Ansgar Lohse, Stefan Lüth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24086391/?tool=EBI