Inhibitory modulation of cytochrome c oxidase activity with specific near-infrared light wavelengths attenuates brain ischemia/reperfusion injury

Abstract The interaction of light with biological tissue has been successfully utilized for multiple therapeutic purposes. Previous studies have suggested that near infrared light (NIR) enhances the activity of mitochondria by increasing cytochrome c oxidase (COX) activity, which we confirmed for 81...

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Bibliographic Details
Main Authors: Thomas H. Sanderson, Joseph M. Wider, Icksoo Lee, Christian A. Reynolds, Jenney Liu, Bradley Lepore, Reneé Tousignant, Melissa J. Bukowski, Hollie Johnston, Alemu Fite, Sarita Raghunayakula, John Kamholz, Lawrence I. Grossman, Karin Przyklenk, Maik Hüttemann
Format: Article
Language:English
Published: Nature Portfolio 2018-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-21869-x