Rapid response in relapsed follicular lymphoma with massive chylous ascites to anti-CD19 CAR T therapy using Piggy Bac: A case report

Rapid response in relapsed follicular lymphoma with massive chylous ascites to anti-CD19 CAR T therapy using Piggy Bac: A case report

CD19-directed chimeric antigen receptor (CAR) T cell therapy has been shown to achieve a considerably durable response in patients with refractory or relapsed B cell non-Hodgkin lymphomas, as seen from the results of Zuma-1, Zuma-5, and other clinical trials. Most of these CARs were generated by len...

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Bibliographic Details
Main Authors: Yan Zhang, Zhicai Lin, Faliang Zhang, Xiuxiu Chen, Yaping Yang, Xin Fu, Zhong Li, Yan Sun, Qijun Qian
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
non-viral gene transfer
Piggy Bac
follicular lymphoma
relapsed
CD-19 directed
chimeric antigen receptor T cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1007210/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.1007210/full

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