Network pharmacology to explore the mechanism of scutellarin in the treatment of brain ischaemia and experimental verification of JAK2/STAT3 signalling pathway

Abstract Scutellarin is used to treat brain ischaemia. However, its underlying mechanism of action remains unclear. This study aimed to elucidate the potential mechanism of action of scutellarin in brain ischaemia through network pharmacology and experimental verification. The JAK2/STAT3 signalling...

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Bibliographic Details
Main Authors: Qiu-Ye Jia, Hao‑Lun Chen, Zhi Qi, Xiao‑Li‑Na Zhang, Li-Yang Zheng, Teng-Teng Liu, Yun Yuan, Li Yang, Chun‑Yun Wu
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-33156-5